Another firm, Novavax starts late-stage trial of covid-19 vaccine in US, Mexico
London, Dec. 29, 2020 (AltAfrica)-Novavax Inc has begun a large late-stage study of its experimental COVID-19 vaccine in the United States, the drug developer said on Monday, after delaying the trial twice due to issues in scaling up the manufacturing process.
Novavax’s shot will become the fifth Covid-19 vaccine to enter final-stage testing in the U.S., and if results are positive it could receive authorization sometime during 2021. Public-health officials say that despite the introduction of the first two Covid-19 vaccines in the U.S., additional vaccines will be needed to meet demand and control the pandemic.
The company didn’t say when it expects to generate results from the new study, but it will likely be spring at the earliest. Studies of the first two vaccines from Pfizer Inc. and Moderna Inc. took nearly four months for results to become available.
Novavax is starting a new clinical trial of up to 30,000 people in the U.S. and Mexico to test whether its experimental Covid-19 vaccine safely protects people from the disease https://t.co/w2kf3pfV8u— The Wall Street Journal (@WSJ) December 28, 2020
It will enrol up to 30 000 volunteers across about 115 sites in the United States and Mexico, with two-thirds of them receiving the shot 21 days apart and the rest getting placebo, the company said.
Novavax lags behind other drug-makers in the global race for COVID-19 vaccine, with shots from Pfizer and Moderna authorised for emergency use in the United States.
But experts have said more than one vaccine would be needed to end the pandemic that has killed over 1.7 million people globally.
Novavax has signed supply agreements with several countries and is set to provide 60 million doses to the UK, where a late-stage study is under way.
The interim data from the trial is expected in the first quarter of 2021.
It is also preparing to deliver 100 million doses to the United States by January after it was awarded $1.6 billion for developing and testing its potential vaccine.
Novavax is also running a fully enrolled Phase 2b trial in South Africa and a Phase 1/2 continuation in the United States and Australia.
Efficacy data from the trials could be available early next year.