We have found antibody that flushes coronavirus out within four days-California-based biotech company
London, May 17, 2020 (AltAfrica)-A California-based biotech company has announced they believe they have a cure for the coronavirus- an antibody that provides ‘100 per cent inhibition.’
Fox news reports that the antibody named “STI-1499 antibody,” which the San Diego company said can provide “100% inhibition” against COVID-19 could be available months before a vaccine hits the market.
“We want to emphasise there is a cure. There is a solution that works 100 per cent,” Sorrento Therapeutics founder and CEO Dr Henry Ji said. “If we have the neutralising antibody in your body, you don’t need the social distancing. You can open up a society without fear.”
Through their studies, Sorrento screened and tested billions of antibodies they have collected over the past decade. They say this made it possible to identify hundreds of potential antibody candidates that could successfully bind themselves to the spike proteins of the coronavirus.
They found that a dozen of these antibodies demonstrated the ability to block the spike proteins from attaching itself to the human enzyme ACE2, which is the receptor a virus normally uses to enter human cells.
Through further testing, the researchers at Sorrento found that there was one particular antibody that showed to be 100 percent effective in blocking COVID-19 from infecting health cells — STI-1499.
“When the antibody prevents a virus from entering a human cell, the virus cannot survive,” Dr. Ji said. “If they cannot get into the cell, they cannot replicate. So it means that if we prevent the virus from getting the cell, the virus eventually dies out. The body clears out that virus.”
“This puts its arms around the virus. It wraps around the virus and moves them out of the body.”
“Antibodies, in general, have been very effective at bringing virus [levels] down if you’ve had a high burden of infection,” Phyllis Kanki, a professor of immunology and infectious diseases at the Harvard T.H. Chan School of Public Health, said in a recent interview. “There are limitations to how much you can give and for how long.”
The number of Covid-19-related deaths is expected to hit 100,000 by June 1 and a host of medical researchers are scrambling to find antibodies that are effective against the disease.
Scientists are optimistic that they could provide a remedy or preventative care in less time than it would take to develop a vaccine. However, finding a successful antibody or convalescent plasma treatment for Covid-19 presents major challenges.
“The best way to control infectious disease [is] where a vaccine comes in,” Dr Amesh Adalja, a Senior Scholar with the Johns Hopkins University Centre for Health Security tells Fox News. “So, obviously vaccines are going to be much more valuable than any kind of treatment. You don’t need treatment because you don’t get infected.”
It was recently announced Sorrento had partnered with New York-based health care system Mount Sinai to develop an antibody cocktail. Dubbed Covi-Shield, the cocktail will be comprised of three different antibodies and, pending FDA approval, will be used as a prophylactic treatment for people returning to work and those who have been exposed to COVID-19.